next-level-study.com – Penyebab kamu suka overthinking bisa berasal dari berbagai hal, salah satunya adalah kebiasaan begadang. Semakin larut malam, semakin gelap suasana, dan pikiran kita sering kali semakin dalam memikirkan hal-hal yang seharusnya tidak perlu dirisaukan. Yuk, sahabat next level study, simak penyebab overthinking ini dan bagaimana cara mengatasinya!
1. Begadang dan Overthinking: Apa Hubungannya?
Kebiasaan begadang sering menjadi salah satu penyebab kamu suka overthinking. Ketika tubuh lelah dan suasana sekitar sunyi, pikiran kita cenderung bekerja lebih aktif. Hal ini terjadi karena pada malam hari, otak tidak lagi teralihkan oleh kesibukan dan aktivitas siang hari, sehingga ia memiliki lebih banyak waktu untuk “menganalisis” berbagai hal.
Begadang dapat meningkatkan aktivitas otak di bagian yang bertanggung jawab atas emosi dan kecemasan. Ini sebabnya banyak orang merasa lebih gelisah dan cenderung overthinking saat larut malam.
2. Kenapa Semakin Malam Pikiran Semakin Dalam?
Saat malam semakin larut, suasana menjadi lebih tenang dan gelap. Hal ini membuat otak kita bekerja lebih keras untuk mencari hal-hal yang sebenarnya tidak perlu dipikirkan secara berlebihan. Akibatnya, kita malah terpaku pada kekhawatiran, masa lalu, atau hal-hal yang belum tentu terjadi.
Faktor lain yang memengaruhi adalah kurangnya istirahat. Ketika tubuh tidak mendapatkan istirahat yang cukup, otak akan kesulitan mengatur emosi, sehingga kita lebih mudah terjebak dalam pikiran yang berulang-ulang alias overthinking.
3. Penyebab Lain Kamu Suka Overthinking
Selain begadang, ada beberapa faktor lain yang bisa menjadi penyebab kamu suka overthinking, di antaranya:
- Perfeksionisme:
Keinginan untuk selalu sempurna bisa membuat kamu terus memikirkan hal-hal kecil yang sebenarnya tidak perlu dirisaukan. - Trauma masa lalu:
Pengalaman buruk di masa lalu sering kali menjadi penyebab seseorang sulit berhenti memikirkan hal-hal negatif. - Kurangnya kepercayaan diri:
Kurang percaya diri juga bisa menjadi penyebab kamu suka overthinking, dimana kamu cenderung memikirkan banyak hal sebelum mengambil keputusan karena takut salah. - Kelelahan mental:
Jika kamu terus-menerus menghadapi tekanan dan stres, otak akan lebih rentan untuk overthinking.
4. Cara Mengatasi Overthinking di Malam Hari
Jika kamu sering mengalami overthinking saat malam hari, berikut beberapa cara yang bisa kamu coba untuk mengatasinya:
- Kurangi Kebiasaan Begadang:
Cobalah untuk tidur lebih awal dan pastikan kamu mendapatkan waktu istirahat yang cukup. Tidur yang cukup akan membantu otak lebih rileks dan mengurangi kecenderungan overthinking. - Latihan pernapasan:
Ketika pikiranmu mulai terlalu aktif, coba lakukan latihan pernapasan dalam-dalam. Teknik ini bisa membantu menenangkan otak dan mengurangi kecemasan. - Alihkan perhatian:
Daripada terus memikirkan hal-hal yang membuatmu overthinking, coba alihkan perhatian dengan membaca buku ringan atau mendengarkan musik santai. - Tulis apa yang kamu pikirkan:
Menulis bisa menjadi cara efektif untuk melepaskan pikiran yang berputar-putar di kepala. Setelah menuliskan semua yang kamu pikirkan, kamu akan merasa lebih lega. - Tetapkan batas waktu berpikir:
Jika kamu merasa perlu memikirkan sesuatu, coba tetapkan batas waktu, misalnya 10 menit. Setelah itu, alihkan perhatianmu ke hal lain.
Overthinking adalah hal yang wajar, terutama jika kamu sedang mengalami tekanan atau kelelahan. Namun, jika dibiarkan terus-menerus, overthinking bisa berdampak buruk pada kesehatan mentalmu. Penyebab kamu suka overthinking bisa jadi karena kebiasaan begadang yang membuat otak terus bekerja di saat tubuh seharusnya beristirahat.
Sahabat next level study, yuk mulai ubah kebiasaan begadang dan belajar mengelola pikiran dengan baik. Dengan begitu, kamu bisa tidur lebih nyenyak dan bangun dengan perasaan yang lebih segar. Bagaimana nih, ada yang pernah mengalami overthinking karena begadang? Yuk, share pengalamanmu di kolom komentar!
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Erythrozytenvorläufer des Knochenmarks von Patienten mit PV proliferieren in vitro spontan ohne Zusatz von Erythropoietin. Gleichzeitig
ist der EPO-Spiegel bei den meisten Patienten erniedrigt.
Dies spricht für erworbene Mutationen im Bereich des Erythropoietin-Rezeptors beziehungsweise
der dazugehörigen Signalkaskadengene. Bitte melden Sie sich mit einem Konto an, dass Sie als Abonnent ausweist und hinterlegen Sie Ihren vollen Namen in Ihrem Profil, oder registrieren Sie sich neu.
Im Hoden spielt Testosteron eine wesentliche Rolle bei der Spermatogenese.
Über diese androgene Wirkung hinaus werden Sexualverhalten und -aktivität beim Mann beeinflusst.
Dementsprechend vielgestaltig ist die klinische Ausprägung eines
Testosteronmangels. Die Substitutionsbehandlung mit Testosteronpräparaten ist in der Praxis fest
etabliert. Therapienutzen und Risiken müssen jedoch
je nach Indikation sorgfältig abgewogen werden.
Medizinische Präparate (5-Reductase-Hemmer oder hoch
dosiertes Zink in Tablettenform), die die Umwandlung von freies testosteron tabelle in Dihydrotestosteron hemmen, müssen dauerhaft eingenommen werden. In großangelegten Studien konnte bei der
Mehrheit der Männer eine Verminderung des Haarausfalls
beobachtet werden, jedoch wirkt diese Therapie nicht bei allen Betroffenen. Testosteron spielt während der
Pubertät eine wichtige Rolle für die Entwicklung der Geschlechtsorgane und die Ausbildung des männlichen Erscheinungsbildes.
Es sorgt als Neurohormon für Antrieb, Stressverarbeitung,
seelische Ausgeglichenheit und kann das sexuelle Verlangen (Libido) steigern. Es ist wichtig
im Rahmen der Samenproduktion und hat einen muskelaufbauenden Effekt.
In diesem Kommentar sind rassistische, gewaltverherrlichende, beleidigende oder
verleumderische Äußerungen enthalten beziehungsweise es werden falsche Tatsachen behauptet?
Dann beschreiben Sie bitte in kurzer Type das Downside, die Redaktion wird diesen Kommentar genauer prüfen und gegebenenfalls
löschen.
Die PV ist eine hämatologische, klonale Erkrankung,
welche zu der Gruppe der myeloproliferativen Neoplasien (MPN) gehört.
Die PV-Patienten haben ein deutlich erhöhtes Risiko für venöse und arterielle
thromboembolische (auch lebensbedrohliche) Ereignisse.
Zudem besteht bei ihnen ein Risiko für
die Entwicklung einer Myelofibrose, einer Type der MPN mit
einer ungünstigeren Prognose. In seltenen Fällen kann die Erkrankung auch in eine akute myeloische Leukämie (AML) fortschreiten. Gemäss der Klassifikation der Tumorerkrankungen der Weltgesundheitsorganisation (WHO) sowie dem Internationalen Consensus
der Klassifikation (ICC) der MPN aus dem Jahr 2022 gibt es
klare diagnostische Kriterien für die PV (Tab. 1). Prostatakrebszellen sind in der Lage, das Hormon Testosteron für
ihr eigenes Wachstum zu nutzen. Durch Hormonentzug kann es vorübergehend zu einem
Stillstand des Tumorwachstums kommen.
Steht die alleinige Senkung der Thrombozyten zur Diskussion, ist
Anagrelid das Medikament der Wahl (mittlere Dosierung 2 mg täglich).
Dieses Präparat wirkt selektiv auf Megakaryozyten und ist nicht leukämogen.
Nebenwirkungen können Kopfschmerzen und Palpitationen sein (23), die im Allgemeinen nach
4 Wochen wieder abklingen. Aufgrund der oralen Verfügbarkeit, der besseren Verträglichkeit, des geringen Preises und der
Zulassung wird im Allgemeinen die Gabe von Hydroxyharnstoff gegenüber der von Interferon-a bevorzugt.
Konventionelles Interferon-a und pegyliertes Interferon-a (kovalent an einen Polyethylenrest gekoppeltes Interferon-a) verbinden hohe
Wirksamkeit mit fehlendem leukämogenen und tumorogenen Risiko.
IE Interferon-a subkutan (beziehungsweise forty µg pegyliertes Interferon-a) pro
Woche reduziert es Erythrozytose, Splenomegalie und Pruritus.
Allerdings muss die Therapie wegen grippeähnlicher
Symptome, Haarausfall und/oder psychiatrischer Störungen häufig abgebrochen werden (22).
Werden die JAK2-spezifischen Mutationen nicht nachgewiesen und
ist der EPO-Spiegel regular oder erhöht, ist eine PV unwahrscheinlich.
In diesem Fall sollte nach Tumoren, die zu einer EPO-Erhöhung führen können, gesucht und eine primäre Polyzythämie ausgeschlossen werden. Ist die JAK2V617F-Mutation nicht vorhanden und der EPO-Spiegel erniedrigt, sollte danach das Exon 12 auf Mutationen untersucht werden.
Ursache der Testosteron-bedingten Polyglobulie ist
vermutlich eine gehemmte Ausschüttung von Hepcidin, das an der
Regulation des Eisenstoffwechsels beteiligt ist. Aus ungeklärten Gründen erhöht sich außerdem die Erythropoetin-Freisetzung.
Es gibt auch Berichte über eine vermehrte inflammatorische Aktivität unter Testosteron-Substitution – dies könnte eine Erklärung für die beobachtete Leukozytose des Patienten sein. Zunächst jedoch behandelten die
Schweizer Internisten den Patienten auf Grundlage der erhobenen Informationen wie einen Polycythaemia-Patienten.
Er erhielt zur Thrombozytenaggregationshemmung Clopidogrel und wurde mehrfach zur Ader gelassen.
Die JAK2 (Januskinase 2) ist eine zytoplasmatische Tyrosinkinase, die
an der Signaltransduktion verschiedener Zytokine (unter
anderem am EPO-Rezeptor) beteiligt ist. Die Mutation verstärkt die
Aktivität der JAK2 und führt damit zu EPO-unabhängigem Wachstum (Grafik 3).
Diese Mutation ist erworben, weil sie nicht in der Keimbahn nachweisbar ist.
Da Erythrozyten keinen Zellkern mehr besitzen, erfolgt der Nachweis
dieser JAK2V617F-Mutation im peripheren Blut über Granulozyten-DNA.
Verschiedene Nierenfunktionsstörungen können auch ohne
hypoxische Stimuli zu einer Erythrozytose führen.
Diese sekundären Polyzythämien sind eine physiologische Antwort auf
die entstehende Gewebehypoxie. Informieren Sie sich täglich (montags bis freitags) per E-Mail über das aktuelle Geschehen aus
der Gesundheitspolitik und der Medizin. Bestellen Sie den kostenfreien Newsletter des Deutschen Ärzteblattes.
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Individuals with hepatitis, cirrhosis, kidney illness, or a history of liver issues
should keep away from testosterone supplements unless a physician advises otherwise.
Individuals with a historical past of heart disease or stroke should
not take testosterone dietary supplements
unless prescribed by a doctor, and even then, they should be
monitored carefully. Over time, the testicles shrink and cut back their capability
to make testosterone. If a person stops taking supplements abruptly,
their testosterone ranges might drop very low, resulting in withdrawal
symptoms. Testosterone is a hormone, not a typical addictive drug like opioids or alcohol.
Nevertheless, people can still develop psychological dependence on testosterone supplements, especially if they use them
for non-medical causes.
Plus, we still don’t know what the long-term effects of testosterone
alternative therapy could be. That’s why I at all times recommend making an attempt natural testosterone boosters
earlier than resorting to TRT injections. Some testosterone-boosting dietary supplements include
the amino acid D-aspartic acid. Some research assist that D-aspartic acid can increase testosterone production, however other research refute this.
A primary cause is as a end result of many side effects of long-term testosterone
substitute therapy, including a controversial increased danger
of heart illness. While some studies support this, more have proven that there may not be detrimental effects of TRT on heart well being.
The American Urological Affiliation (AUA) and the Endocrine Society additionally suggest that men bear prostate
screening earlier than starting testosterone therapy.
This consists of checking PSA ranges and probably performing a digital rectal examination to feel for prostate abnormalities.
Testosterone dietary supplements can have severe effects on mental well being, together with
temper swings, aggression, anxiety, depression, and
dependancy.
The manufacturer emphasizes that growing the dosage by 1-2 capsules
per day will nonetheless hold you within the protected tolerance zone, although the really
helpful quantity is three drugs. The researchers discovered testosterone levels decreased
by 1.28%, and DHEA decreased by 3.52% each year.
The regular testosterone worth in people varies as a outcome of many components,
similar to age. The American Urological Affiliation defines low testosterone as lower
than 300 nanograms per deciliter (ng/dL).
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If you are experiencing signs of low testosterone, corresponding to erectile dysfunction or a
loss of libido, it could be price speaking to
your doctor about different causes, similar to stress, depression and
nervousness. Along with testosterone boosters, there are many pure methods to pep up your T-levels with diet,
train and different lifestyle adjustments.
So, if you’re on the mistaken facet of 30, dropping energy within the fitness center, struggling to focus at work and have all of the power of a scatter
cushion, hold reading. Testosterone treatment is not suggested for males with prostate or breast most cancers.
Additionally, testosterone remedy may worsen sleep apnea
in older folks. Males with hypogonadism reported improved temper and well-being, and decreased fatigue and irritability.
Research means that this remedy may also be an efficient anti-depressant treatment.
The most common type of side-effect that men are inclined
to expertise when they start utilizing a natural testosterone
complement is often a response on their pores and skin. This usually includes their pores and
skin becoming prone to creating zits, in addition to excessively oily.
When a man lives a sedentary lifestyle and doesn’t consume
a wholesome and balanced food plan, he Is clear muscle a steroid extra
prone to suffer from continual illnesses and also turn out to be obese.
It additionally claims to boost total well-being and endurance, giving aging men a more youthful, important feeling.
Military Sgt. Mark Millich, 26, who said he skilled signs such as anxiousness, dizziness, and slurred speech.
He additionally reported severe sexual unwanted side effects,
together with lowered libido and genital shrinkage. Making Use Of a
testosterone gel or cream to the pores and skin is currently the most secure way to deliver an effective dose of testosterone to a
woman. Since there aren’t any FDA-approved commercial merchandise formulated for women, I rely on transdermal gels from a compounding pharmacy.
If you resolve to attempt testosterone for a libido boost, remember that presently no FDA-approved testosterone preparations are commercially available to be used
in women in the Usa. The business testosterone merchandise
on the market are intended and FDA-approved for males solely.
This article will explore the dangers of testosterone dietary supplements, including
their risks, unwanted aspect effects, and warnings. Many people believe that taking testosterone
is a straightforward way to improve their well being
and look, however they could not fully perceive the potential hurt these merchandise
could cause. In distinction, some of the primary elements
in Check Booster Max, such as Fenugreek have
limited and inconsistent proof supporting their effectiveness in elevating testosterone levels.
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Despite the reality that the incidence of a selection of cardiac arrhythmias
differs between women and men, the underlying
mechanisms of those gender variations have not been clearly recognized.
Stopping TRT would possibly reduce heart assault dangers, particularly if you’re experiencing opposed
cardiovascular results. However, this determination should all the time be made
under the guidance of a healthcare provider to avoid sudden hormone imbalances.
Stress can negatively influence your heart
by raising blood pressure and leading to unhealthy coping mechanisms, like
overeating or smoking. Managing stress is essential when you’re on TRT as a result of stress, combined with the results of the therapy, might enhance your heart
attack risk.
You’ll study what the newest analysis says, what factors may increase your danger, and tips on how to handle
these dangers if you’re on TRT. This way, you can really
feel confident about your remedy choices and know what to expect when it comes to
managing your heart well being while on testosterone substitute remedy.
The goal is to provide clear, easy-to-understand information that answers the most pressing questions men have about TRT
and coronary heart assault dangers. Dr. Lau is the
director of the Cardiometabolic Hormones and Health Clinic in the Women’s Coronary Heart Well Being Program at Massachusetts Basic Hospital, where she cares for patients.
For a few years, most ladies thought that hormone substitute therapy (HRT) might put them at larger risk of heart disease.
Current tips recommend cautious consideration of the potential benefits and risks of testosterone remedy in males with cardiovascular threat
factors. Regular monitoring and individualized treatment plans are
emphasised to attenuate potential antagonistic results.
Some researchers believe that TRT could enhance the risk of coronary heart disease in certain groups of men, particularly those that are older or have pre-existing
coronary heart situations.
Don’t buy medicines that declare to deal with ED however don’t want a prescription. These
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In addition, despite the advantages of post-menopause, long-term safety research utilizing T implants in premenopausal women to treat HSDD still have to be improved.
Although there is no diagnostic value for T deficiency
in women, it is suggested to not prescribe T for postmenopausal girls
with indicators of elevated androgens. This includes the presence of medical symptoms (acne, androgenic alopecia, hirsutism, etc.) or regular T ranges (medium or high ranges) [23].
An common blood level of T and what laboratory parameters must be used to information clinicians in remedy nonetheless
need to be improved.
Over time her sleep worsened and repeat PSG in February 2014 showed an AHI of 46.eight events/h.
Her neck circumference was 44.5 cm and the patient’s body
mass index (BMI) was 30 kg/m2 at that time. The patient was once once more evaluated for extreme daytime
somnolence and snoring, with repeat stage 1 PSG as soon as once more confirming her diagnosis (AHI fifty two events/h, oxygen saturation nadir 84%).
On this study, the speedy eye motion (REM)
AHI was 33 events/h, and the non-rapid eye motion (NREM) AHI was 60.9 events/h.
Her neck circumference was unchanged at 44.5 cm and the BMI was decreased
slightly to twenty-eight.7 kg/m2. Treatment with steady optimistic airway
stress (CPAP) remedy was prescribed, but poorly
tolerated. In September 2016, the patient continued to be nonadherent with CPAP therapy.
Like most things in drugs, the answer is sophisticated and we can’t say something with one hundred pc certainty.
For probably the most part, a well managed TRT regimen does not seem
to increase the danger of growing heart disease, however the concern remains to be
underneath a minimum of some debate. The overwhelming majority of proof
has shown testosterone alternative to be protected for the guts.
Nonetheless, there have been a number of studies (of questionable quality) that have proven an elevated threat.
The available database exhibits no evidence to help that T
treatment in ladies, at physiological levels or barely above, increases any adverse
effects related to CVD risk [67,68]. Two potential research demonstrated a decrease threat of cardiovascular disease (CVD) in women with endogenous T levels on the greater reference quintiles [61,62].
Studies of various kinds of T administration (subcutaneous implant, transdermal
patch, spray, or gel) do not present worsening
in lipid ranges, CRP, glycated hemoglobin, or insulin sensitivity.
In a big randomized managed trial, the transdermal T patch didn’t
increase any antagonistic results on lipids, insulin resistance, and CRP in postmenopausal girls compared to
the placebo [63].
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